Surface-modified protein nanospheres as potential antiviral agents.
نویسندگان
چکیده
A novel application of surface-modified protein nanospheres as potential antiviral agents is illustrated. By using a single-step sonochemical process, bovine serum albumin nanospheres were generated, whose surface was covalently conjugated with mercaptoethane sulfonate to chemically and electrostatically mimic cellular heparan sulfate. The nanospheres effectively inhibited HSV-1 infection.
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ورودعنوان ژورنال:
- Chemical communications
دوره 48 67 شماره
صفحات -
تاریخ انتشار 2012